$121.2M in expenses

Path's global health programs division works in partnership with governments and communities to turn proven health innovations into real-world solutions that reach the people who need them most. We strengthen primary health care systems by expanding access to lifesaving tools like malaria preventives and HIV services. We focus on building evidence, improving efficiency, and supporting local health workers - often using digital tools and data to guide smarter decisions. Rather than delivering care directly, we equip health systems to do it better, faster, and more equitably. Our goal is integrated, person-centered care that spans diseases and geographies, making care more accessible, effective, and aligned with the needs of the people it serves. (continued on schedule o)in 2024, path's global health programs division:- reached 9.1 million people with quality health care. - strengthened 93 local partners.key achievements include, but are not limited to:- malaria prevention and surveillancepath's malaria control and elimination partnership in africa (macepa) launched the four-year macepa v grant, expanding its technical support across seven countries. The team supported national malaria programs in the central african republic, the democratic republic of the congo (DRC), ethiopia, the gambia, nigeria, senegal, and zambia, advancing priorities in surveillance, community case management, data use, and strategic planning. Activities included tailored operational planning, analytic and modeling support, surveillance system assessments, and capacity strengthening for national malaria programs.through the reach global malaria project, path supported seasonal prevention campaigns that reached over 2 million children across mali and togo with lifesaving medicine. The project also partnered with national programs in seven countries to improve service delivery and quality of care.- oxygen therapy and equipment accessto ensure medical oxygen reaches patients who need it, path launched a centralized procurement pilot across 14 countries. The new model cut transaction costs by 26% and reduced lead times by up to six months, helping hospitals keep essential systems running in countries across latin america, the middle east, and sub-saharan africa.in the DRC, we also helped medical schools integrate oxygen therapy into their core curriculum and launched a new hands-on training center at the university of kinshasa, equipping hundreds of future doctors with lifesaving respiratory care skills.- strengthening primary health carein ukraine, path expanded hepatitis c services through the unitaid-funded hepc3p project, supporting community-led approaches at opioid treatment centers. This included new self-testing tools, peer-led research, and increased access to harm reduction services.in indonesia, with support from the gates foundation, we helped local health officials improve how people experience primary care by connecting services around individuals rather than diseases.

$107.7M in expenses

Path's product development division makes sure the right health products reach the people who need them - affordably, effectively, and equitably. We develop vaccines, diagnostics, medical devices, and drug formulations for low-resource settings - from early-stage research through licensure, quality testing, and introduction. As a product development partnership, we ACT as the glue - connecting private-sector manufacturers, national health programs, and communities. We make sure lifesaving health products are designed for real-world conditions, not just high-income markets - because health equity begins with access.(continued on schedule o)in 2024, path's product development division:- reached 9.4 million people with quality health care. - strengthened 153 local partners. Key achievements include, but are not limited to:- polio eradicationpath led the global development and delivery of novel oral polio vaccine type 2, a safer, more genetically stable vaccine designed to stop outbreaks caused by vaccine-derived strains. More than 1 billion doses have now been administered worldwide. Path received the innovating for impact award from the global health technologies coalition for its leadership of this effort. In the DRC, path helped launch the congo river strategy, reaching remote communities by canoe to vaccinate children living along the riverbanks.- safer malaria treatment with g6pd testingpath helped co-develop the first point-of-care test for g6pd deficiency to receive world health organization (who) prequalification. The standard g6pd test uses a simple finger prick and delivers results in under two minutes, providing safer treatment of p. Vivax malaria and reducing risk of dangerous drug reactions, especially for women with intermediate deficiency levels.- improving diagnosis and care for sick childrenthrough the tools for integrated management of childhood illness project, path introduced pulse oximeters and digital decision-support tools to clinics in tanzania, kenya, senegal, and india. The tools improved care for over 200,000 children and supported training for more than 1,400 health workers.- vaccine innovation through microarray patches (maps)path supported human factors evaluations of two map candidates for measles-rubella vaccination in kenya, nepal, and the DRC. These needle-free, heat-stable patches were widely accepted by providers and caregivers. If scaled, they could help reach 80 million additional children and prevent 35% more measles cases between 2030 and 2040.- progress in cervical cancer preventionpath generated critical evidence for a single-dose HPV vaccine schedule using cecolin, a low-cost, who-prequalified vaccine. Ghana approved cecolin in 2024 and is now working toward local production, thereby advancing the african union's goal to produce 60% of its vaccines on the continent by 2040.

$43.8M in expenses

In the asia, middle east, and europe (amee) region, we partner with countries to tackle urgent health challenges and expand access to care. We work at every level, from communities to national governments, bringing science, technology, and partnerships closer to where change happens. From expanding HPV vaccination in bangladesh to improving HIV services in ukraine, we tailor our solutions to local needs and build resilient, equitable health systems.in 2024, path's amee region division:- reached 18.2 million people with quality health care.- strengthened 99 local partners. (continued on schedule o)key achievements include, but are not limited to:- bangladeshpath supported the delivery and monitoring of HPV vaccination campaigns to improve vaccine coverage among adolescent girls and prevent cervical cancer.- cambodiapath conducted a feasibility study to create a sustainable one health architecture to enable evidence-based decision support for prevention, early detection, and response of infectious diseases.- fijipath is a formal technical assistance partner for digital health to fiji's ministry of health and the only international nongovernmental organization to join fiji's national digital health technical advisory group. With the world bank, path led a regional digital health landscape analysis across pacific island nations, including fiji, tuvalu, kiribati, and solomon islands.- indiapath strengthened disease surveillance systems for vector-borne diseases and enhanced training for climate-resilient health systems. We launched phixai, a new platform focused on using artificial intelligence (AI) responsibly in health systems, advanced rice fortification to improve nutrition outcomes, and improved the case finding and treatment of acute encephalitis syndrome.- myanmarfollowing cyclone mocha, path helped restore and strengthen community-based mental health and psychosocial services, particularly for women and children affected by displacement and trauma.- nepalpath supported newborn nutrition, including through the establishment and support of human milk banks. Path strengthened the digital reporting systems for immunization.- sri lankapath supported the development of an implementation plan for sri lanka's digital health blueprint and adapted the fortified rice quality management system to support school meal programs and improve child nutrition. - ukrainepath supported the expansion of national e-health services and delivery of HIV, tuberculosis (TB), and maternal mental health services in war-affected areas.- vietnampath helped develop early warning systems for climate-sensitive diseases and integrated these tools into primary health care, ensuring they reach communities most affected by changing environmental conditions.

$44.7M in expenses

Africa regionin the africa region, we partner with countries to deliver health programs that respond to local priorities, from malaria and HIV to vaccines, emergency preparedness, and digital health. We work at every level, from communities to national governments, providing technical support that strengthens existing systems rather than creating new ones. Our focus is on sustainability, equity, and impact, while also investing in strong operations and staff support so our teams thrive across africa's diverse contexts. By combining local insight with global innovation, we help build resilient health systems and improve lives with science, technology, and trusted partnerships. Key 2024 achievements include, but are not limited to: - ethiopiapath helped reopen 14 conflict-damaged health posts, reconnecting 70,000 people to essential services.- kenyapath supported community health workers to screen over 100,000 people for TB and HIV, helped secure new legislation to sustain frontline care, and launched africa's largest AI clinical trial using large language models to support health workers with real-time decision-making. - mozambiquepath advanced a new home-based model for disability screening that tripled access to rehabilitation services for children.- multicountrypath deepened collaboration with africa centres for disease control and prevention by supporting 20 countries to improve disease surveillance through the mpox initiative and build stronger digital infrastructure for epidemic response. Path advanced integrated care for chronic diseases, supporting hypertension screening for over 5 million people in ghana, rwanda, and senegal, and launching new services for diabetes and kidney disease. Other: advocacy & public policyat path's center for advocacy and public policy, we work to ensure everyone can access the health services and innovations they need to thrive. We partner with policymakers in countries like kenya, south africa, and the united states - and on the global stage - to drive investments and policies that support primary health care, maternal and child health, immunization, and innovation. We also support local advocacy partners by translating evidence into clear messages, building coalitions, and sharing knowledge. In 2024, our efforts led to new policies, increased funding, and stronger local capacity to shape health agendas and improve health systems around the world. Key 2024 achievements include, but are not limited to: - expanding access to lifesaving health products and servicespath helped to identify high-priority medical products and build local capacity in kenya and south africa, thereby advancing regional self-reliance.path helped drive progress toward a unified regulatory environment by supporting two additional countries to ratify the african medicines agency treaty. In kenya, path worked with local officials to develop county-level tools that help track and improve primary health care services. Globally, path led a coalition of more than 40 organizations in aligning advocacy strategies for maternal and child health and contributed to new who guidance that streamlines the approval of lifesaving medical products.