$3.8M in expenses

Research - each year aftd invests in the science that will drive discovery and development of accurate diagnostics and the first therapeutics for FTD. To that end, aftd awarded eight grants during fy25, including three pilot grants awarded through the aftd pathways for hope pilot grant program.aftd delivered three awards through the accelerating drug discovery program in collaboration with addf. DR. Jeffrey rothstein of johns hopkins university and his team will use the award to evaluate a novel therapeutic to correct a problem at the heart of FTD associated with the accumulation of the protein TDP-43.(continuted in schedule o)aftd awarded three holloway postdoctoral fellowships - one to a researcher working on a project targeting contributions to white matter hyperintensities in bahavioral variant FTD, another to a researcher working on leveraging a large GRN family to identify resilience factors in FTD, and the last to develop an educational support group program for latino and hispanic caregivers. Aftd also awarded a clinical research training scholarship to investigate the molecular role of specific inclusions in FTD-als, funded through the generous support of the holloway family fund, with additional support from the american brain foundation in collaboration with the american academy of neurology.aftd continued to support the FTD disorders registry, an electronic database that collects information about the FTD experience from persons diagnosed and FTD care partners. This essential source of first-hand accounts will help inform researchers and clinicians, and will spur innovation that will lead to better diagnoses and therapies for people living with FTD. At the end of fy25, 8,537 people had joined the registry.in collaboration with the FTD disorders registry, aftd presented one perspectives in FTD research webinar addressing FTD research 2024. It was our most popular webinar for the fy25 and had a 63% attendance rate.

$2.4M in expenses

Education and supportsupport - aftd understands the challenges that FTD presents to patients and their families, and works hard to develop unique resources and information that will improve quality of life for those living with FTD. Aftd staff responded to 4,203 helpline inquiries in fy25, a 7 percent increase over fy24. As of june 30, 2025, there are 118 aftd-affiliated support group facilitators leading 98 groups across the united states. Aftd awarded 659 comstock grants (travel, respite, and quality of life grants) to FTD caregivers and persons diagnosed. Education and information -- aftd collaborates with a growing number of partners each year to educate healthcare professionals about FTD, with a goal of speeding our way toward accurate diagnosis and effective disease management and treatment. Aftd's 2025 education conference, held in person in denver and online via livestream, drew 1,195 attendees combined. The conference featured experts familiar with FTD and the aftd community to comprehensively discuss content pertinent to people living with or affected by FTD, as well as healthcare professionals seeking greater understanding of this disease. Aftd offered 10 expert-led educational webinars, including one with the FTD disorders registry and two webinars that offered continuing education credits to viewers. Aftd also published four issues of the partners in FTD care newsletter for health professionals.

$3.3M in expenses

Advocacy and awareness - our community is leading the way to send the message that dementia is a multi-faceted disease that can occur at a young age and begin with symptoms unrelated to memory. Aftd is working hard to ensure that this message is heard in washington DC and other seats of power, where decisions about research funding and services are made. Aftd's advocacy action center mobilizes advocates across our community by providing clear guidance on how to take action in support of legislative, policy, and regulatory changes to improve quality of care and quality of life for people with FTD and their families. As of fy25, 2,259 individuals are raising their voices through our advocacy platform.