$117.3M in expenses

Concern & awareness - see schedule o for detailsconcern & awareness alzheimer's is a progressive, degenerative and ultimately fatal disease. Too few americans understand the current and future economic impact of alzheimer's. Already more than 7 million americans are living with alzheimer's and as many as 12 million people are providing unpaid care and support. And this massive group is in need of information and resources.advertising is an investment that guarantees named placements of the alzheimer's association's core messages. Alzheimer's association advertisements are available in multiple formats: television, print, radio, digital and others, such as out of home. Prior to investing in ad development, the alzheimer's association undertook careful research to identify our media target audience, understand their preference and, in turn, develop each ad based on their and other feedback. Each ad strives to communicate the realities of alzheimer's disease and to ensure that people know that the alzheimer's association is available to help, day or night, and how to contact us or get involved in the fight against alzheimer's disease.the alzheimer's association has invested in education campaigns and initiatives to increase concern about alzheimer's disease and awareness of the alzheimer's association communicating our role as leaders of the cause. The alzheimer's association undertakes numerous initiatives and creates marketing and advertising campaigns to increase awareness about alzheimer's disease and the association as the leading voluntary health organization in alzheimer's care, support and research. The initiatives and campaigns take place either year-round or during specific time periods. Key messages include the importance of early detection, resources for people with alzheimer's and their families, and the societal impact of the disease. Millions of constituents participated in our programs in local communities and on-line.the alzheimer's association has identified the hispanic/latino community as a nationwide priority diverse audience, further driving our strategy to provide spanish-language materials. We also recognize that chapters and other departments across pillars may identify the need for materials in languages spoken by communities within their geographic locations. The alzheimer's association has developed the translation strategy and process guide to assist departments in meeting their local translation needs while maintaining consistent alzheimer's association messaging.

$106.9M in expenses

Research - see schedule o for detailsresearchthe alzheimer's association is at the forefront of the alzheimer's scientific field, globally connecting researchers in the quest to find methods of diagnosis, treatment, prevention and ultimately cures for all the diseases that cause cognitive impairment and dementia. The alzheimer's association implements an aggressive global research and science program strategically designed to accelerate progress by fostering innovation, identifying and closing critical knowledge gaps, developing and disseminating tools, and nurturing scientific talent.as the largest nonprofit funder of alzheimer's and dementia research, the alzheimer's association is committed to accelerating the global progress of new treatments, preventions and, ultimately, a cure. With over 20 funding programs offered across the entire spectrum of science to investigators at all career-levels, the alzheimer's association is currently committed to over $450 million to over 1,200 projects in 56 countries. In addition, the alzheimer's association's part the cloud funding program is designed to accelerate the transition of potential therapies from laboratory testing to clinical trials. Since 2012, the part the cloud initiative has raised nearly $90 million to accelerate scientific progress in funding the most promising early phase clinical studies.the alzheimer's association seeks to fund and advance best-in-class research and works with collaborators around the globe from all sectors to hasten this progress. An example of the high risk, high reward funding, the alzheimer's association funded the development pittsburgh compound b (pib), the first radiotracer capable of showing beta-amyloid in the living brain during a positron emission tomography (pet) scan. This sppurred significant investment in this area of research, leading to three now FDA-approved tracers for amyloid pet. Identifying beta-amyloid in the living brain can be used to support the diagnosis of alzheimer's and also lets researchers determine if an experimental drug successfully decreases this hallmark alzheimer's protein providing invaluable information about disease progression. Another example, the alzheimer's association u.s. Study to protect brain health through lifestyle intervention to reduce risk (u.s. Pointer) is a two-year clinical trial to evaluate whether lifestyle interventions that simultaneously target many risk factors protect cognitive function in older adults who are at increased risk for cognitive decline. U.s. Pointer is the first study of its kind to be conducted in a large diverse and representative group of americans across the country. This landmark study reported out the topline results in july 2025, demonstrating that two lifestyle interventions targeting a combination of physical activity, improving nutrition, cognitive and social challenge and health monitoring improved cognition in older adults at risk of cognitive decline. Further, while both interventions improved cognition, the cognitive benefits were even greater for the partiicpants in the more structured intervention group, helping to protect thinking and memory from the normal decline that often comes with aging over the two-year period of the study. The alzheimer's association has also launched the nation's first alzheimer's network for treatment and diagnostics (alz-net) which is a voluntary health care provider-enrolled patient network that collects clinical and safety data for patients treated with new FDA-approved alzheimer's disease therapies and tracks the long-term health outcomes associated with their use in real-world settings.alz-net is a resource for evidence gathering, information sharing and education across the clinical and research communities to help improve brain health outcomes for patients.the alzheimer's association has been a catalyst and convener for more than 40 years. The alzheimer's association offers year-round opportunities for the scientific community to network and learn about alzheimer's and dementia research. Events include the alzheimer's association international conference (aaic) - the world's largest meeting dedicated to advancing dementia science - and a variety of in-person and virtual conferences, symposia and other events. A part of the aaic menu of year-round events includes:-aaic neuroscience next: a global, no-cost conference that aims to support and showcase the next generation of alzheimer's and dementia researchers and clinicians. The program is presented in a "hybrid hub" format that connects both global and local communities.-aaic advancements offers a forum for focused information and discussion on topics critical to moving alzheimer's and dementia research forward. Topics have included apoe, immunity, modernizing diagnosis, exploring equity in diagnosis and more.-aaic satellite symposium meetings spotlight alzheimer's and dementia research within a specific region, including meetings in africa, latin america and more. Select aaic satellite symposia are hosted in partnership with the global brain health institute.convening goes beyond meetings, and bringing together the broader ecosystem through common areas of interest is essential to driving forward progress. A clear example, the alzheimer's association international society to advance alzheimer's research and treatment (istaart) is a diverse global network of scientists, clinicians and dementia professionals. Members of this professional organization share common goals: the pursuit of knowledge, collaboration and breakthroughs to advance the research and treatment of alzheimer's disease and other dementias.sharing of scientific information and discourse happens in a number of venues, including aaic, the aaic family of meetings, istaart, but also in scientific publications. Alzheimer's & dementia: the journal of the alzheimer's association is the leading peer-reviewed, monthly journal in alzheimer's and dementia. In addition, the alzheimer's association's journal family includes three other open-access journals. Collaboration is essential when researching treatments and diagnostic biomarkers for alzheimer's disease and other neurodegenerative diseases. The alzheimer's association convenes several consortia where researchers from industry, academia, and government scientists are advancing our understanding, diagnosing, and treatments for alzheimer's and all other dementia. Examples of this include the alzheimer's association research roundtable (aarr), the alzheimer's association business consortium (aabc), and the global biomarker standardization consortium (GBSC).

$106.7M in expenses

Care, support and risk reduction - see schedule o for detailscare, support and risk reduction the programs and services of the alzheimer's association are designed to provide education, information, support, and resources in order to help individuals with alzheimer's, their families, and caregivers, to navigate the long and complicated journey through alzheimer's disease and other dementias. The alzheimer's association's programs and services are offered in person, by phone and online. In chapters throughout the country, constituents can attend education programs and support groups, receive personalized care consultation, and engage in early-stage programs.the alzheimer's association works to improve the quality of dementia care on every level, by convening experts to set standards of care, by educating individuals and their caregivers, by providing training and continuing education for care professionals, and by partnering with health systems and public agencies to enact systems change. Unique programming opportunities include direct training to providers through essentialz, video-based education through project echo and care provider community coaching. In addition, the joint commission memory care certification, developed in collaboration with the alzheimer's association, helps nursing care centers and assisted living communities improve care for people living with dementia.the alzheimer's association's website (WWW.alz.org) receives more than 31 million visits a year. Online programs include on-demand education programs, an online community, an interactive brain tour (available in 15 languages), access to comprehensive disease information, portals in spanish, chinese, vietnamese, japanese, and korean; a virtual library, a safety center, and a section developed specifically for people living with alzheimer's, with input from people in the early stages of alzheimer's disease and their care partners.in order to meet the needs of constituents who rely on the web for information and support, the alzheimer's association offers a robust caregiver center. Community resource finder connects people with local resources, support groups, community programs and services. Families and caregivers can access alznavigator, an innovative tool to help caregivers and people with dementia evaluate their needs, create a customized action plan and link to information, support and local resources for individuals living with alzheimer's. Alzconnected is a free online community/message board for everyone affected by alzheimer's or another dementia. Individuals living with alzheimer's, caregivers, family members and friends can ask questions, get advice and find support.the alzheimer's association free 24/7 helpline (800.272.3900) (https://WWW.alz.org/help-support/resources/helpline) is available around the clock, 365 days a year. Specialists and master's-level clinicians received over 204,000 calls, emails and online chats, offering confidential support and information to people living with dementia, caregivers, families and the public. The service is partially funded by a five-year, $10 million federal grant awarded by the department of health and human services administration for community living.the alzheimer's association convenes an early-stage advisory group whose members raise awareness on a national level, advocate for the cause, and provide guidance and review of programs and services. The alzheimer's association also convenes experts from across academia, research and industry, hosting critical conversations aimed at advancing research and policy as well as improving the care and support available to those living with or facing alzheimer's or another dementia. These included the alzheimer's association innovation roundtable, the research roundtable, dementia care provider roundtable and dementia care navigation roundtable. The alzheimer's association supports brain health across the lifespan, including promoting risk reduction for cognitive decline and dementia through the development and dissemination of 10 healthy habits for your brain, community-based and volunteer-led educational programing, and national leadership through the bold public health center of excellence on dementia risk reduction. This information is disseminated to broad and diverse audiences via the web, social media, the association's 24/7 contact center, chapter networks and health departments nationwide.

$44.8M in expenses

Other (diversity, equity & inclusion, public policy, & mission engagement)public policy: as alzheimer's disease threatens to bankrupt families, businesses and our healthcare system, scientists are moving closer to finding better treatments that could alter the course of the disease. The alzheimer's association advocates for public policies aimed at advancing research toward better therapies, detection, methods of prevention and ultimately a cure, as well as for better care and resources, and health and long-term coverage to ensure high quality cost effective care for people with alzheimer's disease and their families. More than 600,000 grass roots alzheimer's association advocates speak up for the needs and rights of people with alzheimer's and their families, and encourage congress to increase funding for research and care. Public policy activities also include collaborating with other organizations to improve quality care and raise awareness of key issues.diversity, equity & inclusion: the alzheimer's association believes that engaging diverse perspectives is critical to achieving health equity, meaning that all communities have a fair and just opportunity for early diagnosis and access to risk reduction and quality care. Underrepresented and underserved communities are disproportionately impacted by alzheimer's and dementia, and yet are less likely to be diagnosed; less likely to be recruited to participate in research; and less likely to have access to care and support services. This is unacceptable and must change. We are leading the way by developing strategic partnerships with trusted national and local organizations to create a pathway to greater health equity, mission engagement and inclusion for everyone. The alzheimer's association is building an organizational culture of understanding while pursuing diversity, equity and inclusion through education and policies. The alzheimer's association is committed to providing all communities with resources and education to realize our vision of a world without alzheimer's and all other dementia.mission engagement: the alzheimer's association focuses on mission-related products and solutions development to reach more people in new and innovative ways, supporting all those facing alzheimer's and other dementia, providing or influencing their care and those accelerating science.the total expenses, grants, and revenue related to the programs described above on part iii, line 4d are as follows: